hpss2026pp39-45 20260929101500000 hyperscienceij@gmail.com:rcrl hyperscienceij@gmail.com WEB-FORM Hyperscience in Psychology and Social Science HPSS 31158625 09 2026 2 3 Sharif Mustaffa Retired Professor, Counselling Centre, University Technology Malaysia, Skudai, 81310 Johor, Malaysia Chemotherapy can generate substantial anticipatory anxiety because patients may expect nausea, vomiting, fatigue, pain, loss of control, and disruption of family or occupational roles. These reactions are shaped not only by treatment-related physical effects but also by cognitive appraisal, previous experiences, information obtained from others, and the perceived ability to cope. This article presents an expanded brief counselling framework that integrates cognitive-behavioral methods with structured problem solving, self-practice, mindfulness, and acceptance-based strategies. The framework is designed for use before and during chemotherapy and emphasizes realistic cognitive reappraisal rather than simple positive thinking. It also incorporates distress screening, collaborative goal setting, practical coping plans, and referral when symptoms exceed the scope of brief counselling. Contemporary psycho-oncology guidance supports routine assessment of psychological distress and the use of evidence-based psychosocial interventions, including cognitive-behavioral and mindfulness-based approaches. The proposed framework is intended as a clinically practical model rather than as evidence of a newly tested intervention. Future research should evaluate its feasibility, cultural adaptability, and effects on anxiety, psychological flexibility, treatment engagement, and quality of life. 09 2026 39 45 10.55672/hpss2026pp39-45 https://hscience.org/index.php/hpss